/* header */
header {
    width: 100%;
    z-index: 9999;
    position: absolute;
    background-color: rgba(255,255,255,.75);
    max-width: 1320px;
    margin: 0 auto;
    top: 0;
    left: 0;
    right: 0;
}

#header-content {
    width: 100%;
    max-width: 1320px;
    margin: 0 auto;
    padding: 5px 0 0 0;
    height: auto;
    position: relative;
    border-right: 1px solid #707070;
    border-left: 1px solid #707070;
}

    #header-content.addPadding {
        padding: 25px 0 0 0;
    }

    #header-content .slideIn {
        display: none;
        align-items: center;
        padding: 0 39px 0;
        max-width: 1057px;
        flex-wrap: wrap;
    }

        #header-content .slideIn .close .closeSlide {
            border: none;
            background: none;
        }

        #header-content .slideIn .slideText {
            flex: 1 1 70%;
        }

        #header-content .slideIn .close .closeSlide:hover #Ellipse_1, #header-content .slideIn .closeSlide:hover #Ellipse_1 {
            stroke: #707070;
        }

        #header-content .slideIn .close .closeSlide:hover #X, #header-content .slideIn .closeSlide:hover #plus {
            fill: #707070;
        }

        #header-content .slideIn .close #open {
            display: none;
        }

.closedIndication {
    display: none;
    flex: 1 1 100%;
    order: 3;
    margin-bottom: 25px;
}

    .closedIndication .closeSlide.closed {
        display: flex;
        align-items: center;
    }

    .closedIndication .closeSlide.closed {
        border: none;
        background: none;
    }

        .closedIndication .closeSlide.closed span {
            color: #94348c;
            font: 900 14px/14px 'Muli', Arial;
            line-height: 16px;
            display: inline-block;
            margin: 10px 15px 0 0;
        }

.video-container {
    position: relative;
}
/* content (general) */
#article-bg-wrapper {
    max-width: 960px;
    width: 100%;
    margin: 0 auto;
    overflow: hidden;
    position: fixed;
    top: 172px;
    left: 0;
    z-index: -1;
}

.no-js #article-bg-wrapper {
    left: calc((100vw - 960px)/2);
    height: 100vh;
    top: 118px;
}

#article-bg {
    background: url(/Content/img/content-bg.png) 0 -120px no-repeat;
    margin-left: 132px;
    margin-right: 50px;
    height: 100%;
    width: 100%;
}

article {
    margin: 0 auto;
    width: 100%;
}

.no-js article {
    height: calc(100vh - 118px);
}

.no-scroll article .wrapper,
.no-scroll article footer {
    pointer-events: none;
}

article .wrapper {
    background: rgba(148, 52, 140, 0.1);
}

.marginAuto {
    margin: 0 auto !important;
}

.wideFigureWidth {
    max-width: 992px;
}

.center {
    text-align: center;
}

.purpleTable-FAQ-pl {
    padding-left: 17px !important;
}

.container {
    max-width: 1320px;
    margin: 0 auto;
    background-color: #fff;
    border-right: 1px solid #707070;
    border-left: 1px solid #707070;
    padding-bottom: 30px;
    padding-top: 1px;
}

header p.usage {
    font: 600 14px/14px 'Muli', Arial;
    line-height: 16px;
    color: #000000;
}

    header p.usage:first-of-type {
        margin-bottom: .5rem;
    }

    header p.usage:last-of-type {
        margin-top: .2rem;
    }

header ul.usage-PU {
    font: 600 14px/14px 'Muli', Arial !important;
    line-height: 16px !important;
    color: #000000 !important;
}

li.usage {
    font: 600 14px/14px 'Muli', Arial;
    line-height: 16px;
    color: #000000;
}

/* ISI + widget */
#isi {
    clear: both;
    margin: 0 75px;
}

    #isi > h2 {
        color: #94348c;
        font-size: 24px;
        font-family: Arial, sans-serif;
        font-weight: bold;
        margin: 1.33em 0 .65em;
    }

    /*#isi .firstParagraph {
        display: block;
    }*/

    #isi a:hover {
        text-decoration: underline;
    }

#isi-widget {
    height: 150px;
    width: 100%;
    position: fixed;
    overflow: hidden;
    z-index: 1000;
    bottom: 0;
    -webkit-box-shadow: 0px -4px 5px rgba(1, 1, 1, 0.35);
    -moz-box-shadow: 0px -4px 5px rgba(1, 1, 1, 0.35);
    box-shadow: 0px -4px 5px rgba(1, 1, 1, 0.35);
}

    #isi-widget.expanded {
        z-index: 99999999;
    }

.no-js #isi-widget {
    display: none;
}

#isi-widget.minimized {
    height: 32px;
}

#isi-widget-bar {
    background: #E1C3DC;
    height: 44px;
    display: flex;
    align-items: center;
}

#isi-widget-bar-content {
    max-width: 978px;
    width: 100%;
    margin: 0 auto;
    position: relative;
}

    #isi-widget-bar-content h2 {
        cursor: pointer;
        color: #94348c;
        font: 700 20px/16px 'Muli', Arial;
        margin: 0;
        margin-left: 170px;
        position: relative;
        padding-right: 39px;
    }

        #isi-widget-bar-content h2:after {
            content: '\002B';
            position: absolute;
            right: 210px;
            font-size: 30px;
            top: 0;
        }

        #isi-widget-bar-content h2.firstVisit:after {
            right: 239px;
        }

.expanded #isi-widget-bar-content h2:after {
    content: '\2212';
}

#isi-widget-content-wrapper {
    background: #fff;
    overflow: hidden;
    height: 127px;
}

#isi-widget.expanded #isi-widget-content-wrapper {
    overflow-y: scroll;
}

#isi-widget-content {
    width: 100%;
    max-width: 1320px;
    margin: 0 auto;
}



    #isi-widget-content .isi-clone {
        margin-left: 130px;
        margin-right: 50px;
        padding-right: 40px;
        padding-left: 40px;
    }

.win #isi-widget-content .isi-clone {
    padding-left: 48px;
}

.widgetOnly {
    display: none;
}

#isi-widget-content .visitedIsi.widgetOnly {
    display: none;
}

.visitedIsi {
    display: none;
}

.firstVisit {
    display: none;
}

#isi .desktopOnly.notWidget {
    display: block;
}

#isi-widget-content .widgetOnly.firstParagraph {
    display: block;
}

#isi-widget-content .widgetOnly.firstVisit {
    display: none;
}

#isi-widget-bar-content .visitedIsi .flex {
    align-items: center;
    width: 100%;
    display: flex;
}

    #isi-widget-bar-content .visitedIsi .flex span {
        display: block;
        flex: 1 1 50%;
        width: 50%;
    }

        #isi-widget-bar-content .visitedIsi .flex span:last-of-type {
            margin-left: 185px;
            ;
        }

#isi-widget-bar-content h2.visitedIsi {
    margin-left: 0;
}

#isi-widget .isi-clone .flex {
    display: flex;
}

    #isi-widget .isi-clone .flex .col-flex {
        flex: 1;
        flex-wrap: wrap;
    }

.isi-clone .flex .col-flex {
    flex-wrap: wrap;
}

#isi-widget .isi-clone .flex .col-flex:first-of-type {
    margin-right: 75px;
}


.isi-clone h2 {
    color: #94348c;
    font: bold 20px/22px Arial;
    margin: 0.5em 0;
}

    .isi-clone h2 + ul {
        margin: 0 0 0 1em;
        padding: 0;
    }

.isi-clone ul + h2 {
    margin-top: 1.5em;
}

.isi-clone p {
    margin: 0.75em 0;
    color: #000;
}

.isi-clone-p {
    margin: 10px 0px 9px 0px !important;
}

.isi-clone h2 + p {
    margin-top: 0.5em;
    color: #000;
}

.isi-clone p + h2 {
    margin-top: 1.5em;
}

.isi-heading {
    margin-top: 1.5em !important;
}

.isi-clone li {
    color: #94348c;
    margin-bottom: 0.2em;
}

    .isi-clone li span {
        color: #000;
    }

#isi-widget-content .isi-clone li span, #isi-widget-content .isi-clone p {
    color: #000;
}
/* footer */
footer {
}

#footer-main-nav {
    display: none;
}

.no-js #footer-main-nav {
    display: block;
}

#footer-main-nav a {
    background: url(/Content/img/footer-main-nav-bg.png) repeat-x;
    box-shadow: 0px 1px 1px 0px rgba(126, 6, 116, 0.004);
    border-bottom: 1px solid #efe0ed;
    border-top: 1px solid #fff;
    color: #fff;
    display: block;
    font: 18px/20px 'Muli', Arial, sans-serif;
    padding: 12px 20px;
    text-decoration: none;
}

#footer-main-nav > a.active {
    background: #d5b4dd !important;
    color: #58495b !important;
}

#footer-main-nav a span {
    background: url(/Content/img/footer-main-nav-arrow-down.png) right bottom no-repeat;
    background-size: 15px 12px;
    display: block;
    width: 100%;
}

#footer-main-nav a.open span {
    background-image: url(/Content/img/footer-main-nav-arrow-up.png);
}

#footer-main-nav a.open.active {
    background-color: #521f4f;
    color: #fff;
}

#footer-main-nav div {
    display: none;
}

.no-js #footer-main-nav div {
    display: block;
}

#footer-main-nav div a {
    background: #d5b7dd;
    border-bottom: 1px solid #000;
    color: #58595b;
    padding-left: 40px;
}

    #footer-main-nav div a:hover, #footer-main-nav div a.active {
        background: #521f4f;
        color: #fff;
    }

#footer-wrapper {
    background: rgba(148, 52, 140, 0.1);
    float: left;
    min-height: 264px;
    height: auto;
    width: 100%;
}

.no-cssgradients #footer-wrapper {
    background: rgb(240,240,240);
}

#footer-content {
    margin: 0 auto;
    max-width: 1320px;
    border-right: 1px solid #707070;
    border-left: 1px solid #707070;
    position: relative;
    width: 100%;
    background-color: #ededec;
}

    #footer-content .row {
        margin: 0 auto;
    }

        #footer-content .row .copy {
            margin-bottom: 0;
            padding-bottom: 1em;
        }

    #footer-content .references {
        margin: 0;
        padding-bottom: 40px;
        padding-top: 20px;
    }

    #footer-content nav {
        padding-bottom: 40px;
    }

        #footer-content nav + p {
            margin-top: 0;
            max-width: 835px;
        }

            #footer-content nav + p + p {
                max-width: 620px;
            }

        #footer-content nav a {
            color: #94348C;
            font: 700 11px 'Muli', Arial, sans-serif;
            text-decoration: underline;
            padding-right: 5%;
            text-transform: uppercase;
            letter-spacing: 1.24px;
        }

            #footer-content nav a:hover {
                color: #FF661B;
            }

        #footer-content nav div {
            display: inline;
        }

    #footer-content p {
        color: #787878;
        font: 14px/18px Arial;
    }

    #footer-content .astellas-logo {
        position: absolute;
        bottom: 32px;
        right: 70px;
        background: url(/Content/img/footer-logo.png) no-repeat;
        width: 160px;
        height: 44px;
        display: block;
        background-size: 160px 44px;
    }

.desktop-codeline {
    display: inline;
}

.mobile-codeline {
    display: none;
}


@media only screen and (max-width: 1150px) {
    #footer-content p {
        width: calc(100% - 230px);
    }
}

@media only screen and (max-width: 767px) {
    #footer-content p {
        width: 100%;
    }
}

@media only screen and (max-width: 960px) {
    #footer-content nav {
        padding-bottom: 120px;
    }

    #footer-content p {
        margin: 0px;
    }
}

/* modal window */
.modal {
    position: fixed;
    overflow: auto;
    z-index: 10000;
    top: 0;
    right: 0;
    bottom: 0;
    left: 0;
    display: none;
}

.modal-overlay {
    background: rgba(74,74,74,0.72);
    position: fixed;
    top: 0;
    right: 0;
    bottom: 0;
    left: 0;
    -webkit-backface-visibility: hidden;
}

.modal-content {
    background: #fff;
    box-shadow: 0px 0px 10px 0px rgb(0 0 0 / 75%);
    padding: 40px;
    position: relative;
    margin: 5% auto;
    max-height: 57em;
    max-width: 560px;
    width: 85%;
}

    .modal-content h2 {
        color: #94348C;
        font-size: 24px;
        font-family: 'Muli', Arial, sans-serif;
        line-height: 1;
        margin: 0;
    }

    .modal-content p {
        color: #707070;
        font: 16px/20px 'Muli', Arial, sans-serif;
        padding-bottom: 20px;
    }

        .modal-content p + p {
            font-weight: bold;
            color: #FF00F5;
        }

    .modal-content .cta {
        display: inline;
        width: 200px;
        padding: 10px;
        margin-bottom: 0;
        background: #94348C;
        text-transform: uppercase;
        font-size: 13px;
        border-radius: 10px;
    }

        .modal-content .cta.change-btn {
            margin-right: 50px;
        }

.modal button:focus {
    outline: none !important;
    border: 1px solid #8f2b8c;
    box-shadow: 0 0 10px #8f2b8c;
}

#exit-modal .modal-content {
    max-width: 780px;
    margin-left: -390px;
}

#exit-modal .modal-container > div {
    text-align: right;
}

#exit-modal .modal-content a:not(.cta) {
    color: #ffffff;
    font-size: 20px;
    line-height: 25px;
}

#exit-modal .modal-content a.cta {
    display: inline-block;
    margin-left: 58px;
}

.spinner {
    margin: 30px auto;
    width: 50px;
    height: 30px;
    text-align: center;
    font-size: 10px;
}

    .spinner > div {
        background-color: #fff;
        height: 100%;
        width: 6px;
        display: inline-block;
        -webkit-animation: stretchdelay 1.2s infinite ease-in-out;
        animation: stretchdelay 1.2s infinite ease-in-out;
    }

    .spinner .rect2 {
        -webkit-animation-delay: -1.1s;
        animation-delay: -1.1s;
    }

    .spinner .rect3 {
        -webkit-animation-delay: -1.0s;
        animation-delay: -1.0s;
    }

    .spinner .rect4 {
        -webkit-animation-delay: -0.9s;
        animation-delay: -0.9s;
    }

    .spinner .rect5 {
        -webkit-animation-delay: -0.8s;
        animation-delay: -0.8s;
    }

.fullWidthTable table {
    width: 800px;
}

.muliTable td {
    font: 18px/20px 'Muli', Arial, sans-serif;
}

.muliTableSmall td, .muliTableSmall div {
    font: 16px/20px 'Muli', Arial, sans-serif;
}

.center td {
    text-align: center;
}

.noBorder {
    border-top: none;
}

.tableFootnotes p, .footnotes p, .tableFootNote {
    font: 14px/18px Arial;
}

.accordion .footnotes p span {
    font: 14px/18px Arial !important;
}

.underline {
    text-decoration: underline;
}

.spanMobile {
    display: none !important;
}

ul.arial li span {
    font: 18px/22px Arial;
}

.muliLarge strong, .muliLarge span {
    font: 400 20px/24px 'Muli', Arial, sans-serif;
}

.extraSpace {
    margin-bottom: 25px !important;
}

.muliTableSmall strong.purple {
    color: #94348C;
}

@media only screen and (min-width: 960px) {
    .tableFootnotes {
        max-width: 1100px;
        min-width: 800px;
        margin: 0 auto;
    }

    #isi-widget-content .widgetOnly.firstParagraph.noDesktop {
        display: none;
    }


    .tableFootNote {
        width: 1100px;
        margin: 1.25em auto;
    }

    .figureWidth {
        margin: 0 auto;
        max-width: 800px;
        min-width: 800px;
    }
}

.small {
    color: #707070 !important;
}

@-webkit-keyframes stretchdelay {
    0%, 40%, 100% {
        -webkit-transform: scaleY(0.4);
    }

    20% {
        -webkit-transform: scaleY(1.0);
    }
}

@keyframes stretchdelay {
    0%, 40%, 100% {
        transform: scaleY(0.4);
        -webkit-transform: scaleY(0.4);
    }

    20% {
        transform: scaleY(1.0);
        -webkit-transform: scaleY(1.0);
    }
}

@media only screen and (max-width: 960px) {
    header {
        background: url("../../Content/img/Lighthouse_CoreArt_CMYK_ForCover_04.jpg") no-repeat center -100px;
    }

    #header-wrapper {
        background-color: rgba(255,255,255,.75);
    }

    article {
        padding-top: 245px;
    }

    h1 {
        margin-top: 0 !important;
        padding-top: 1em;
    }

    .customTable span {
        font: 16px/18px 'Muli', Arial, sans-serif;
        color: #707070;
    }

        .customTable span.no-wrap {
            margin: 25px 15px 0;
            display: block;
        }

    .customTable .noBorder {
        margin-bottom: 2px;
    }

    table .light th {
        color: #707070;
    }

    .noPadding {
        padding: 0;
    }

    #video-container h2 {
        font: 700 22px/26px 'Muli', Arial, sans-serif !important;
    }

    .pharmacokinetics .marginTop {
        margin-top: 25px;
    }

    .dosingTableMobile, .dosingTableMobile table {
        margin: 0;
        width: 100%;
    }

    .dosingTable-FAQ-ml table {
        margin-left: -16px !important;
    }

    .DosingTableGreen-PU table {
        margin-right: -48px !important;
    }

    .dosingTableMobileForphase1 {
        max-width: 100px !important;
        margin-left: -20px !important;
    }

    .invasive td.title {
        width: 40%;
    }

    .invasive td.centered:first-of-type {
        width: 20%;
    }

    .invasive td.centered:last-of-type {
        width: 30%;
    }

    .dosingTableMobile .padding {
        padding: 15px;
        display: block;
    }

    .dosingTableMobile .paddingForphase1 {
        padding-top: 10px !important;
        padding-left: 0px !important;
        padding: 0px;
    }

    .small {
        font: 14px/16px 'Muli', Arial !important;
    }

    .invasive td.centered.muliLarge strong {
        font: 800 14px/16px 'Muli', Arial;
    }

    .dosingTableMobile span {
        color: #707070;
    }

    #header-content > a img {
        width: 173px;
    }


    #header-utility nav ul {
        position: absolute;
        top: -23px;
        width: 100%;
        left: 0;
    }

        #header-utility nav ul li {
            width: 32%;
            text-align: center;
            padding-right: 0;
            margin-right: 0;
        }

            #header-utility nav ul li.isi-link {
                width: 36%;
            }

            #header-utility nav ul li.pi-link {
                width: 33%;
            }

            #header-utility nav ul li.patient-link {
                width: 29%;
            }

            #header-utility nav ul li a {
                display: block;
                font-size: 14px;
                padding-top: 8px;
            }

                #header-utility nav ul li a br {
                    display: none;
                }

                #header-utility nav ul li a span {
                    display: inline;
                    color: inherit;
                    font-size: inherit;
                }

    #isi-widget-bar {
        height: 52px;
    }

    #header-utility nav > a {
        top: 40px;
        width: 172px;
    }

        #header-utility nav > a + a {
            right: 180px;
            width: 172px;
        }

    #header-utility > div {
        width: 150px;
        left: 200px;
    }

    .no-js #article-bg-wrapper {
        left: 0;
        width: calc(100vw - 60px);
    }

    #isi {
        margin: 0 20px;
    }

    #isi-widget .isi-clone .homepage, #isi-widget-bar-content .homepage {
        display: none;
    }

    #header-main-nav a span {
        text-align: left !important;
        width: 75%;
        display: block;
        margin: 0 auto;
    }

    #isi-widget .isi-clone .flex, #isi-widget-bar-content .landing .flex {
        display: flex;
        flex-wrap: wrap;
    }


        #isi-widget .isi-clone .flex .col-flex {
            flex: 1 1 100%;
            width: 100%;
        }

    #isi-widget .isi-clone .homepage, #isi-widget-bar-content .homepage {
        display: block;
    }

    .fullWidthTable table {
        width: 100%;
        min-width: auto;
        margin: 0;
    }

    .fullWidthTable {
        margin: 0;
    }

        .fullWidthTable table th {
            font: 22px/26px 'Muli', Arial, sans-serif;
        }

    .tableFootnotes {
        max-width: 100%;
        min-width: 100%;
    }

    .spanMobile {
        display: inline !important;
    }

        .spanMobile br {
            display: block;
        }
}

@media only screen and (max-width: 480px) {
    article {
        padding-top: 210px;
    }
}

@media only screen and (max-width: 767px) {
    #footer-content {
        padding-bottom: 20px;
    }

        #footer-content .astellas-logo {
            position: relative;
            right: auto;
            margin-top: 16px;
            background: url(/Content/img/footer-logo-mobile.png) no-repeat;
            width: 129px;
            height: 36px;
            background-size: 129px 36px;
        }
}

@media only screen and (max-width: 960px) {
    body {
        height: 100%;
    }

        body.no-scroll #header-wrapper {
            padding-right: 0;
        }

    #article-bg-wrapper {
        display: none;
    }

    #light {
        display: none !important;
    }

    .no-js article {
        height: auto;
    }

    #main-content {
        background: #ffffff;
        margin: 0;
        padding-left: 16px;
        padding-right: 16px;
        padding-top: 0;
        padding-bottom: 20px;
    }

    .home #main-content {
        background: none;
    }

    #isi-widget {
        height: 115px;
    }

    #isi-widgetexpanded {
        z-index: 99999;
    }
    /*#isi-widget.expanded { bottom: auto; top: 150px; }*/
    /*#isi-widget.minimized { height: 41px; }*/
    /*#isi-widget-bar { height: 77px; }*/
    #isi-widget-bar-content h2 {
        margin-left: 16px;
    }

        #isi-widget-bar-content h2:after {
            right: 16px;
            font-size: 30px;
        }

    #isi-widget-content .isi-clone {
        margin: 0;
        padding-left: 16px !important;
        padding-right: 16px;
    }

    .isi-clone h2 {
        margin-bottom: 0.25em;
    }

        .isi-clone h2 + p {
            margin-top: 0;
        }

    #footer-main-nav {
        display: block;
    }

    .no-js #footer-wrapper {
        padding-bottom: 0;
    }

    #footer-content nav a {
        display: block;
        padding-bottom: 2em;
        float: left;
        width: 100%;
    }

    #footer-content nav .mobile-col-1 {
        width: 50%;
        float: left;
        display: block;
    }

    #footer-content nav .mobile-col-2 {
        width: 50%;
        float: right;
        display: block;
    }

    #footer-content nav span {
        display: none;
    }

    #footer-content .references {
        padding-bottom: 24px;
    }

    .desktop-codeline {
        display: none;
    }

    .mobile-codeline {
        display: inline;
    }

    #exit-modal .modal-content {
        width: auto;
        max-width: 780px;
        margin: 0 auto;
        top: 55px;
        left: 22px;
        right: 22px;
        padding: 30px 14px 15px 14px;
    }

        #exit-modal .modal-content h2 {
            font-size: 20px;
            line-height: 25px;
        }

        #exit-modal .modal-content p {
            font-size: 14px;
            line-height: 16px;
        }

    .modal-content a.close-btn {
        width: 22px;
        height: 22px;
        top: 11px;
        right: 11px;
    }

    #exit-modal .modal-content a:not(.cta) {
        font-size: 14px;
    }

    #exit-modal .modal-content a.cta {
        font-size: 14px;
        max-width: 120px;
        margin-left: 30px;
        padding: 8px;
    }

    #mobile-sticky {
        display: block;
    }
}

}

@media only screen and (max-width: 640px) {
    .modal-content {
        margin-left: 0;
        left: 5%;
        width: 90%;
    }
}

@media only screen and (max-width: 480px) {
    #header-utility nav > ul li {
        width: 28%;
    }

        #header-utility nav > ul li a {
            letter-spacing: -.5px;
        }

    #header-utility span {
        bottom: -24px;
        line-height: 1;
        text-align: right;
        width: 120px;
    }

    #header-content .logo {
        width: 52%;
    }

        #header-content .logo img {
            max-width: 200px;
        }
}

@media only screen and (max-width: 430px) {
    #isi-widget-bar-content h2 {
        padding-top: 3px;
        line-height: 18px;
    }

        #isi-widget-bar-content h2:after {
            top: 12px;
        }
}


@media only screen and (max-width: 376px) {
    #isi-widget {
        height: 120px;
    }
}

@media only screen and (max-width: 321px) {
    #isi-widget {
        height: 135px;
    }

    #header-content .logo {
        width: 52%;
    }

        #header-content .logo img {
            max-width: 154px;
        }

    article {
        padding-top: 213px;
    }
}



nav .active .astellaDesktop {
    display: none !important;
}

nav {
    position: relative;
}

a {
    color: #94348C;
    text-decoration: none;
}

.menu,
.submenu,
.subnav {
    list-style-type: none;
    margin: 0;
}

nav .subnav {
    display: flex;
    width: 100%;
    padding: 0 15px;
}

    nav .subnav li:first-of-type {
        padding-left: 0;
    }

    nav .subnav li {
        margin-bottom: 0;
        flex: 1;
        padding: 0 .5%;
        display: flex;
        justify-content: center;
    }

.logo {
    font-size: 20px;
    padding: 7.5px 10px 0 0;
    order: 2;
}

.menu ul li {
    margin-bottom: 0;
    padding-left: 0;
}

.has-submenu:hover {
    cursor: pointer;
}

li.logo {
    margin-bottom: 0;
}

.label {
    order: 0;
    color: #94348C;
    font-size: 12px;
    padding: 5px;
}

.subnav {
    order: 1;
    margin: 0;
}

    .subnav li a, .subnav li span {
        font: 600 13px/16px 'Muli', Arial;
        color: #2B2B2B;
    }



.active .item.astellaMobile {
    background-color: #EFEFEF;
    display: flex;
    flex-wrap: wrap;
    justify-content: center;
    align-items: center;
    margin-bottom: 0;
    padding: 25px 0;
    height: 270px;
}

.active .Menu.fixed .item.astellaMobile {
    max-height: 400px;
}

.item.active a, .item.active a:after .nav {
    display: flex;
    align-items: center;
    justify-content: center;
}

.active .item.astellaMobile .nav {
    display: flex;
    align-items: center;
    justify-content: center;
}

    .active .item.astellaMobile .nav a, .active .item.astellaMobile .content a {
        color: #676765;
        font-size: 14px;
        font-weight: 200;
        width: 100%;
        border-bottom: none;
    }

    .active .item.astellaMobile .nav .astella img {
        max-width: 80px;
    }

    .active .item.astellaMobile .nav .astella:after {
        content: "|";
        margin: 0 25px;
    }

.active .item.astellaMobile .content {
    text-align: center;
    color: #707070;
    height: 100%;
}

    .active .item.astellaMobile .content img {
        max-width: 30px;
    }

    .active .item.astellaMobile .content strong {
        display: block;
        margin: 10px 0;
    }

    .active .item.astellaMobile .content span {
        display: block;
    }

.menu.active .item.astellaMobile .answers a {
    color: #A8284C;
    padding-top: 12px;
}

.showUnderlineHome .activeHomepage {
    text-decoration: underline;
}

.item.button {
    padding: 9px 5px;
}

.item:not(.button) a:hover,
.item a:hover::after {
    color: #676765;
}
/* Mobile menu */
.menu {
    display: flex;
    flex-wrap: wrap;
    justify-content: space-between;
    align-items: center;
}

    .menu li a {
        display: block;
        padding: 10px 5px;
    }

    .menu li span {
        padding: 10px 5px;
        display: block;
    }

    .menu li.subitem {
        margin-top: 0;
    }

    .menu.active .Menu li.item:not(.astellaMobile) a {
        color: #fff;
        font-size: 20px;
        font-weight: 600;
        min-height: 50px;
        display: flex;
        align-items: center;
    }

        .menu.active .Menu li.item:not(.astellaMobile) a span {
            color: #fff;
            font-size: 20px;
            font-weight: 600;
            padding: 0;
        }

    .menu li.subitem a {
        padding: 15px;
        color: #fff;
    }

        .menu li.subitem a.active, .active .item a.active {
            text-decoration: underline;
        }

        .menu li.subitem a:hover {
            text-decoration: underline;
            color: #fff;
        }

    .menu li.subitem {
        background: transparent;
    }

.toggle {
    order: 3;
    color: #fff;
    margin-right: 19px;
    transition: all 500ms cubic-bezier(0.55, 0, 0.1, 1);
}

    .toggle button {
        color: #fff;
        padding: 13px 20px !important;
        background-color: #94348C;
        font-size: 20px;
        border: none;
        width: 100%;
        text-transform: uppercase;
        min-height: 50px;
    }

        .toggle button i {
            margin-left: 7px;
        }

.active .toggle button {
    background-color: #1E988A;
}

.item.button {
    order: 2;
}

.item {
    order: 4;
    width: 100%;
    display: none !important;
}

.Menu {
    order: 4;
    display: none;
    transition: all 500ms cubic-bezier(0.55, 0, 0.1, 1);
}

.active .item {
    display: block !important;
    margin-bottom: 0;
}

    .active .item a {
        display: block;
        border-bottom: 1px solid #fff;
    }

.menu.active .Menu {
    margin: 0;
    background: #94348C;
    width: 100%;
    display: block;
    overflow-y: scroll;
}

    .menu.active .menu.fixed {
        height: calc(100% + 1px);
    }

.button.secondary {
    /* divider between buttons and menu links */
    border-bottom: 1px #444 solid;
}
/* Submenu up from mobile screens */
.submenu {
    display: none;
}

.submenu-active .submenu {
    display: block;
}

.has-submenu i {
    font-size: 12px;
}

.has-submenu > a:after {
    font-family: "Font Awesome 5 Free";
    font-size: 12px;
    line-height: 16px;
    font-weight: 900;
    content: "\f078";
    color: #94348C;
    padding-left: 5px;
}

.has-submenu.submenu-active > a:after {
    content: "\f077";
    color: #676765;
}

.subitem a {
    padding: 10px 15px;
}

.submenu-active {
    border-radius: 3px;
}

    .submenu-active .submenu {
        background-color: #B157A9;
    }

.Menu.fixed {
    position: fixed;
    top: -75px;
    background-color: #94348C;
    width: 100%;
    border-top: none;
    color: #fff;
    left: 0;
    display: flex;
    justify-content: center;
    min-height: 50px;
    margin: 0;
    min-height: 55px;
}

.menu.active .Menu.fixed .onlyFixed {
    padding-top: 50px;
    border-top: 1px solid #fff;
}

.Menu.fixed.nav-down {
    top: 0;
}

.Menu.fixed + .toggle.fixed {
    position: fixed;
    top: -65px;
    max-height: 51px;
    width: 100%;
}

.Menu.fixed.nav-down, .toggle.fixed.nav-down {
    top: 0 !important;
}


#isi-widget-content .notWidget {
    display: none !important;
}

.subnav li.button {
    background-color: #94348C;
    border-radius: 10px;
    padding: 0px 35px;
    margin-left: 10px;
}

    .subnav li.button:hover {
        background-color: #622a62;
    }

    .subnav li.button a {
        color: #fff;
    }

@media all and (max-width:1160px) {

    .answers {
        display: none;
    }

    .nav .astella:after {
        display: none;
    }
}


@media all and (max-width: 960px) {
    .has-submenu.submenu-active a:after {
        color: #fff !important;
    }

    .subnav {
        background-color: #94348C;
    }

        .subnav li a, .subnav li span {
            color: #fff;
        }

    .has-submenu > a:after {
        font-family: "Font Awesome 5 Free";
        font-weight: 900;
        content: "\f078";
        color: #fff;
        font-size: 18px;
        padding: 5px;
        margin-left: auto;
        text-decoration: none;
    }

    .flex.visitedIsi {
        flex-wrap: wrap;
    }

    .menu.active .Menu li.item.active a span {
        text-decoration: underline;
    }
}

@media all and (min-width: 1300px) {
    nav .subnav li {
        padding: 0 1%;
    }

        nav .subnav li.after a:after, nav .subnav li span:after {
            content: "|";
            margin: 0 0 0 11px !important;
            color: #fff;
        }
}
/* Desktop menu */
@media all and (min-width: 1160px) {
    /*#isi .firstParagraph {
            display: none !important;
        }*/

    #isi-widget-content .widgetOnly.firstParagraph {
        display: none;
    }

        #isi-widget-content .widgetOnly.firstParagraph.showDesktop {
            display: block;
        }

    .notWidget.mobileOnly {
        display: none !important;
    }

    .notWidget.desktopOnly {
        display: block !important;
    }

    .Menu.fixed {
        position: fixed;
        top: -75px;
        background-color: #94348C;
        width: 100%;
        border-top: none;
        color: #fff;
        left: 0;
        display: flex;
        justify-content: center;
    }

    .menu {
        align-items: flex-start;
        background: none;
    }

    .logo {
        order: 0;
    }

    .item {
        order: 2;
        position: relative;
        display: block !important;
        width: auto;
        padding: 0 28px 0 0;
    }

    .label {
        order: 3;
    }

    .button {
        order: 2;
    }

    .Menu li {
        margin-bottom: 0;
        padding-bottom: 10px;
    }

        .Menu li.item ul li.subitem a {
            padding: 0;
        }

        .Menu li.subitem:first-of-type {
            padding: 15px 1em;
        }

        .Menu li.subitem:last-of-type {
            padding: 0 1em 15px 1em;
        }


    /*.item a.active, .subitem a.active {
        text-decoration: underline;
    }*/

    header .item.active a:after {
        display: inline;
        text-decoration: none;
    }

    .menu li.subitem {
        padding-left: 1em;
    }

    .submenu-active .submenu, .has-submenu:hover .submenu {
        display: block;
        position: absolute;
        left: 0;
        top: 101%;
        background: rgba(103,103,101, .70);
        min-width: auto;
        white-space: nowrap;
    }

        .submenu-active .submenu a {
            color: #fff;
        }

            .submenu-active .submenu a:hover {
                color: #fff;
                text-decoration: underline;
            }

    .menu li.item a {
        font-weight: 600;
        padding: 10px 0;
    }

        .menu li.item a span.underlineSpan {
            font-weight: 600;
            padding: 10px 0;
            color: #94348C;
            text-decoration: none;
            padding: 0;
            font-family: 'Muli', "Arial", sans-serif;
            display: inline;
            font-size: 16px;
        }

    .menu li.item.active a span.underlineSpan, .item.active a:after {
        color: #676765;
    }

    .toggle {
        display: none;
    }

    .submenu-active {
        border-radius: 0;
    }

    .astellaMobile {
        display: none !important;
    }

    .Menu {
        display: flex;
        grid-column: 2 /4;
        padding-top: 16px;
        border-top: 1px solid #707070;
        margin-left: 0;
    }

        .Menu .onlyFixed {
            display: none !important;
        }

        .Menu.fixed .onlyFixed {
            display: block !important;
        }

        .Menu .mobileOnly {
            display: none !important;
        }

        .Menu.fixed li a, .Menu.fixed li a span.underlineSpan {
            color: #fff;
        }

        .menu .Menu.fixed li.item.active a span.underlineSpan {
            color: #fff;
            text-decoration: underline;
        }

        .Menu.fixed li a:hover {
            color: #fff;
            text-decoration: underline;
        }

        .Menu.fixed .has-submenu > a:after {
            color: #fff;
        }

    .menu {
        display: grid;
        gap: 0 30px;
        grid-template-columns: 325px 1fr 242px;
        grid-template-rows: 63px 27px auto;
    }

    .logo {
        grid-column: 1;
        grid-row: 1 / 3;
        padding-left: 32px;
        padding-top: 0;
    }

    nav .subnav {
        grid-column: 2;
        grid-row: 1 / 2;
        border-top-right-radius: 10px;
        border-bottom-right-radius: 10px;
        padding: 0;
    }


        nav .subnav li:first-of-type span {
            padding: 13px 0 13px 5px;
        }

        nav .subnav li.after a:after, nav .subnav li span:after {
            content: "|";
            margin: 0 6px;
            color: #2b2b2b;
        }

        nav .subnav li span {
            display: block;
        }

        nav .subnav li a, nav .subnav li span {
            font-size: 13px;
            padding: 14px 0 13px 0;
            font-weight: 600;
            cursor: pointer;
        }

            nav .subnav li a:hover, nav .subnav li span:hover {
                text-decoration: underline;
            }

    nav .astellaDesktop {
        grid-column: 3;
        grid-row: 1 / 2;
        border-radius: 10px;
        background-color: rgba(255,255,255,0.8);
        border: 1px solid #707070;
        display: flex !important;
        padding: 0;
        justify-content: center;
        margin-right: 15px;
        max-height: 41.5px;
    }

        nav .astellaDesktop:hover {
            background-color: #CECECE;
        }

        nav .astellaDesktop .nav {
            display: flex;
            padding: 10px 5px 13px;
            position: relative;
        }


    .astellaDesktop .nav .astella {
        align-self: center;
        max-width: 80px;
        display: block;
    }

    .astellaDesktop .nav span:before {
        content: "|";
        color: #A8A7A7;
        margin: 0 10px;
        font: 400 24px/25px Arial, sans-serif;
    }

    .astellaDesktop .nav .answers span {
        font-weight: 300;
        color: #A8284C;
        font-size: 14px;
        position: relative;
        padding-top: 12px;
        display: block;
    }


    .astellaDesktop .nav .answers {
        background: transparent;
        border: none;
        display: flex;
        align-items: center;
    }

    .astellaDesktop .nav.active .med_info_content {
        display: block;
    }

    .astellaDesktop .nav .answers span:after {
        content: "\f107";
        font-family: "Font Awesome 5 Free";
        font-size: 12px;
        color: #707070;
        padding-left: 3px;
        font-weight: 600;
    }

    .astellaDesktop .nav.active .answers span:after {
        content: "\f106";
    }

    .med_info_content {
        position: absolute;
        display: none;
        background-color: #fff;
        width: 208px;
        padding: 16px;
        top: 42px;
        border: 1px solid #707070;
        border-radius: 10px;
        z-index: 99999;
    }

        .med_info_content img {
            max-width: 20px;
        }

        .med_info_content p {
            font-size: 14px;
            color: #707070;
        }

            .med_info_content p a {
                font-weight: 200;
                font-size: 12px;
            }

    nav .subnav li {
        flex: none;
    }

    blockquote {
        display: flex;
        justify-content: center;
        align-items: center;
    }

    .minHeight {
        min-height: 89px;
    }

    .isi-widget-content-wrapper .notWidget {
        display: none;
    }
}

@media all and (max-width: 1260px) and ( min-width: 1160px) {
    nav .subnav li {
        padding: 0 .2%;
    }

        nav .subnav li:not(:last-of-type) a:after, nav .subnav li span:after {
            margin: 0 2px;
        }

        nav .subnav li a, nav .subnav li span {
            font-size: 1vw;
        }
}

@media all and (max-width: 1205px) and ( min-width: 1160px) {
    .subnav li.button {
        padding: 0px 20px;
    }
}

@media all and (max-width: 1240px) and ( min-width: 1160px) {
    .menu li.item a span.underlineSpan {
        font-weight: 600;
        padding: 10px 0;
        color: #94348C;
        text-decoration: none;
        padding: 0;
        font-family: 'Muli', "Arial", sans-serif;
        display: inline;
        font-size: 15px;
    }

    .item {
        padding: 0px 20px 0px 0px;
    }
}

.STOP {
    display: block !important;
}